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COMPLEMENT C3B INACTIVATOR PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Complement C3b Inactivator Proteins
Descriptor
Spanish
:
Proteínas Inactivadoras del Complemento C3b
Descriptor
Portuguese
:
Proteínas Inativadoras do Complemento C3b
Tree Number:
D12.776.124.486.274.920.325
Definition
English
:
Endogenous
proteins
that inhibit or inactivate
COMPLEMENT C3B
. They include
COMPLEMENT FACTOR H
and
COMPLEMENT FACTOR I
(C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the
down-regulation
of
COMPLEMENT ACTIVATION
and its cytolytic sequence.
Indexing Annotation
English
:
DF: C3B INACT
Pharmacological Action:
Complement Inactivating Agents
History Note
English
:
2006 (1978)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22142
Unique Identifier:
D003180
Occurrence in VHL
:
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